Effectiveness of Ketamine Infusions
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Studies show 60–70% of patients with treatment resistent depression experience significant improvement after a full series of infusions (Correia-Melo et al., 2020).
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In large real-world data, about 56% of patients improved, and nearly 1 in 3 achieved remission (Mindbloom, 2023).
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Clinical trials have reported a 67% improvement rate compared to the placebo (Feder et al., 2021).
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Research demonstrates a 55–70% rapid reduction, often within hours of infusion (Ballard et al., 2019).
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A head-to-head study found 55% of patients improved with ketamine, compared to 41% with ECT—while ketamine had fewer side effects (Anand et al., 2023; Harvard Gazette, 2023).
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Unlike most antidepressants that target serotonin, ketamine acts on glutamate, a key neurotransmitter involved in mood, learning, and memory. This leads to faster results—often within hours or days.
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Ketamine helps your brain form new connections and break out of rigid, negative thought patterns. This "reset" allows for new ways of thinking, feeling, and healing, especially when paired with therapy.
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In a therapeutic setting, ketamine can soften emotional defenses, making it easier to explore trauma, grief, and stuck points that are hard to access in regular talk therapy.
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Ketamine is one of the few treatments shown to rapidly reduce suicidal thinking, even when other medications haven’t worked—making it a powerful tool in crisis situations.
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Many clients report feeling more connected, clear, and emotionally open after treatment. Some describe ketamine as helping them “see the bigger picture,” “feel like themselves again,” or “break out of the fog.”